Dr. Lvov’s laboratory focus is on developing nanotechnology including nanoassembly
of ultrathin organized films, bio/nanocomposites, nano/construction of ordered shells
on tiny templates (drug nanocapsules, shells on microbes and viruses), clay nanotubes
for controlled release of bioactive agents. Yuri Lvov was among the pioneers of the
polyelectrolyte layer-by-layer (LbL) assembly, a nanotechnology method which, after
the first papers in 1993, was followed by many thousands of publications by researchers
from all over the world. LbL nanoassembly has already been used in industrial applications
for eye lens modification, improvement of cellulose fiber for better fabric and paper,
microcapsules for insulin sustained release, cancer drug nanocapsules, and others.
The basic principle of our research is nanoarchitectonic, and we develop: 1) nanoassembly
approach in biomimetic engineering; 2) smart nanocontainers, nanocapsules and nanotubes
for drug targeted and controlled delivery; stem cell and microbe encapsulation; 3)
integrated nano/micro/macro-organized tissue scaffolds (in collaboration with Mark
DeCoster and David Mills).